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KMID : 0387720100210020165
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Korean Journal of Blood Transfusion
2010 Volume.21 No. 2 p.165 ~ p.170
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A Case of Mild Hemolytic Disease of the Fetus and Newborn - The First Case of Anti-Dib Identified on Prescreening Test during Pregnancy -
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Choi Ji-Won
Kim Moon-Jung
Kim Myung-Han
Park Jung-Ran
Kim Hyun-Ok
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Abstract
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The Di(a+b-) phenotype is extremely rare among Caucacians and mostly confined to mongoloids. The clinical significance of anti-Dib is incompletely recognized. The authors report here a mild case of hemolytic disease of the fetus and newborn (HDFN) due to anti-Dib. The mother was Di(a+b-) with anti-Dib, which was detected by antenatal screening. She delivered a Di(a+b+) infant with a positive direct antiglobulin test and mild hemolytic disease. The infant was treated by phototherapy and subsequently recovered without the need for exchange transfusion. We suggest that the screening program as routine prenatal care is necessary.
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KEYWORD
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Anti-Dib, Hemolytic disease of a fetus and newborn, Antenatal screening
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